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1

Specific bisulfite modification of CTG triplet repeats of the androgen receptor gene, a gene associated with the triplet repeat disease X-linked spinal and bulbar muscular atrophy (Kennedy disease)

Kensuke Ochi, Hiroyuki Nozaki, Fumiaki Tanaka, Shingo Kato, Ryuji Fukuzawa, Gen Sobue, Yasuo Fukuuchi, Yoshiaki Toyama, Jun-ichi Hata, Akihiro Umezawa

Journal:

Neuroscience Research Communications

Année:

2001

Langue:

english

Fichier:

PDF, 699 KB

english, 2001

2

Activation of CD44 induces ICAM-1/LFA-1-independent, Ca2+, Mg2+, —independent adhesion pathway in lymphocyte-endothelial cell interaction

Noriko Toyama-Sorimachi, Kensuke Miyake, Masayuki Miyasaka

Journal:

European Journal of Immunology

Année:

1993

Langue:

english

Fichier:

PDF, 2.29 MB

english, 1993

3

Use of isolated mature osteoblasts in abundance acts as desired-shaped bone regeneration in combination with a modified poly-DL-lactic-co-glycolic acid (PLGA)-collagen sponge

Kensuke Ochi, Gouping Chen, Takashi Ushida, Satoshi Gojo, Kaoru Segawa, Hitoshi Tai, Kenju Ueno, Hiroyuki Ohkawa, Taisuke Mori, Akira Yamaguchi, Yoshiaki Toyama, Jun-ichi Hata, Akihiro Umezawa

Journal:

Journal of Cellular Physiology

Année:

2003

Langue:

english

Fichier:

PDF, 596 KB

english, 2003

4

Primary infection of Japanese infants with adult T-cell leukaemia-associated retrovirus (ATLV): Evidence for viral transmission from mothers to children

Shiro Nakano, Yoshiya Ando, Kensuke Saito, Ikuko Moriyama, Motohiko Ichijo, Takenori Toyama, Kazuo Sugamura, Joko Imai, Yorio Hinuma

Journal:

Journal of Infection

Année:

1986

Langue:

english

Fichier:

PDF, 507 KB

english, 1986

5

Surgical treatment of scoliosis using allograft bone from a regional bone bank

Masashi Takaso, Toshiyuki Nakazawa, Takayuki Imura, Masaki Ueno, Wataru Saito, Ryousuke Shintani, Kensuke Fukushima, Masahiro Toyama, Kouji Sukegawa, Takamitsu Okada, Michinari Fukuda

Journal:

Archives of Orthopaedic and Trauma Surgery

Année:

2011

Langue:

english

Fichier:

PDF, 497 KB

english, 2011

6

Two-year results for scoliosis secondary to Duchenne muscular dystrophy fused to lumbar 5 with segmental pedicle screw instrumentation

Masashi Takaso, Toshiyuki Nakazawa, Takayuki Imura, Takamitsu Okada, Masahiro Toyama, Masaki Ueno, Kensuke Fukushima, Wataru Saito, Atsushi Minatani, Gennyo Miyajima, Michinari Fukuda, Naonobu Takahir

Journal:

Journal of Orthopaedic Science

Année:

2010

Langue:

english

Fichier:

PDF, 244 KB

english, 2010

7

Expression profiles of two types of human knee-joint cartilage

Kensuke Ochi, Yataro Daigo, Toyomasa Katagiri, Akihiko Saito-Hisaminato, Tatsuhiko Tsunoda, Yoshiaki Toyama, Hideo Matsumoto, Yusuke Nakamura

Journal:

Journal of Human Genetics

Année:

2003

Langue:

english

Fichier:

PDF, 838 KB

english, 2003

8

Effect of Freeze-Thawing Breast Milk on Vertical HTLV-I Transmission from Seropositive Mothers to Children

Yoshiya Ando, Kazuhiro Kakimoto, Takuo Tanigawa, Kazuo Furuki, Kensuke Saito, Shiro Nakano, Hiratsugu Hashimoto, Ikuko Moriyama, Motohiko Ichijo, Takenori Toyama

Journal:

Année:

1989

Fichier:

PDF, 192 KB

1989

9

Long-term serological outcome of infants who received frozen–thawed milk from human T-lymphotropic virus type-I positive mothers

Yoshiya Ando, Yutaka Ekuni, Yoshinari Matsumoto, Shiro Nakano, Kensuke Saito, Kazuhiro Kakimoto, Takuo Tanigawa, Motohiro Kawa, Takenori Toyama

Journal:

Journal of Obstetrics and Gynaecology Research

Année:

2004

Langue:

english

Fichier:

PDF, 60 KB

english, 2004

10

Vascular responses to 8-nitro-cyclic GMP in non-diabetic and diabetic mice

Yoshiko Tokutomi, Keiichiro Kataoka, Eiichiro Yamamoto, Taishi Nakamura, Masaya Fukuda, Hisato Nako, Kensuke Toyama, Yi-Fei Dong, Khandaker Ahtesham Ahmed, Tomohiro Sawa, Takaaki Akaike, Shokei Kim-Mi

Journal:

British Journal of Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2011

11

Exercise therapy correlates with improving renal function through modifying lipid metabolism in patients with cardiovascular disease and chronic kidney disease

Kensuke Toyama, Seigo Sugiyama, Hideki Oka, Hitoshi Sumida, Hisao Ogawa

Journal:

Journal of Cardiology

Année:

2010

Langue:

english

Fichier:

PDF, 222 KB

english, 2010

12

Improvement effect on endothelial function in patients with congestive heart failure treated with cardiac resynchronization therapy

Koji Enomoto, Hiroshige Yamabe, Kensuke Toyama, Yasushi Matsuzawa, Megumi Yamamuro, Takashi Uemura, Kenji Morihisa, Satomi Iwashita, Koichi Kaikita, Seigo Sugiyama, Hisao Ogawa

Journal:

Journal of Cardiology

Année:

2011

Langue:

english

Fichier:

PDF, 200 KB

english, 2011

13

Preservation of the auditory nerve function after translabyrinthine removal of vestibular schwannoma

Kensuke Kiyomizu, Keiji Matsuda, Meiho Nakayama, Tetsuya Tono, Koji Matsuura, Hirokazu Kawano, Katsuhiro Toyama, Shizuo Komune

Journal:

Auris Nasus Larynx

Année:

2006

Langue:

english

Fichier:

PDF, 162 KB

english, 2006

14

Telmisartan protects against diabetic vascular complications in a mouse model of obesity and type 2 diabetes, partially through peroxisome proliferator activated receptor-γ-dependent activity

Kensuke Toyama, Taishi Nakamura, Keiichiro Kataoka, Osamu Yasuda, Masaya Fukuda, Yoshiko Tokutomi, Yi-Fei Dong, Hisao Ogawa, Shokei Kim-Mitsuyama

Journal:

Biochemical and Biophysical Research Communications

Année:

2011

Langue:

english

Fichier:

PDF, 566 KB

english, 2011

15

Computer simulation of humeral shaft fracture in throwing

Kensuke Sakai, Yoshimori Kiriyama, Hiroo Kimura, Noriaki Nakamichi, Toshiyasu Nakamura, Hiroyasu Ikegami, Hideo Matsumoto, Yoshiaki Toyama, Takeo Nagura

Journal:

Journal of Shoulder and Elbow Surgery

Année:

2010

Langue:

english

Fichier:

PDF, 548 KB

english, 2010

16

Rosuvastatin combined with regular exercise preserves coenzyme Q10 levels associated with a significant increase in high-density lipoprotein cholesterol in patients with coronary artery disease

Kensuke Toyama, Seigo Sugiyama, Hideki Oka, Yuri Iwasaki, Hitoshi Sumida, Tomoko Tanaka, Shinji Tayama, Hideaki Jinnouchi, Kunihiko Matsui, Hisao Ogawa

Journal:

Atherosclerosis

Année:

2011

Langue:

english

Fichier:

PDF, 315 KB

english, 2011

17

Analysis of oxidative stress expressed by urinary level of 8-hydroxy-2′-deoxyguanosine and biopyrrin in atrial fibrillation: Effect of sinus rhythm restoration

Toyama, Kensuke, Yamabe, Hiroshige, Uemura, Takashi, Nagayoshi, Yasuhiro, Morihisa, Kenji, Koyama, Junjiroh, Kanazawa, Hisanori, Hoshiyama, Tadashi, Ogawa, Hisao

Journal:

International Journal of Cardiology

Année:

2013

Langue:

english

Fichier:

PDF, 323 KB

english, 2013

18

Response: Analysis of oxidative stress expressed by urinary level of 8-hydroxy-2′-deoxyguanosine and biopyrrin in atrial fibrillation: Effect of sinus rhythm restoration

Toyama, Kensuke, Yamabe, Hiroshige, Uemura, Takashi, Ogawa, Hisao

Journal:

International Journal of Cardiology

Année:

2013

Langue:

english

Fichier:

PDF, 63 KB

english, 2013

19

Rosuvastatin Ameliorates Early Brain Injury after Subarachnoid Hemorrhage via Suppression of Superoxide Formation and Nuclear Factor-Kappa B Activation in Rats

Uekawa, Ken, Hasegawa, Yu, Ma, Mingjie, Nakagawa, Takashi, Katayama, Tetsuji, Sueta, Daisuke, Toyama, Kensuke, Kataoka, Keiichiro, Koibuchi, Nobutaka, Kawano, Takayuki, Kuratsu, Jun-ichi, Kim-Mitsuyam

Journal:

Journal of Stroke and Cerebrovascular Diseases

Année:

2014

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2014

20

Announcements

Ochi, Kensuke, Mori, Toshiki, Toyama, Yoshiaki, Nakamura, Yusuke, Arakawa, Hirofumi

Journal:

Cancer Treatment Reviews

Année:

1983

Langue:

english

Fichier:

PDF, 130 KB

english, 1983

21

Identification of Semaphorin3B as a Direct Target of p53

Ochi, Kensuke, Mori, Toshiki, Toyama, Yoshiaki, Nakamura, Yusuke, Arakawa, Hirofumi

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 197 KB

english, 2002

22

Pretreatment with rosuvastatin protects against focal cerebral ischemia/reperfusion injury in rats through attenuation of oxidative stress and inflammation

Ma, Mingjie, Uekawa, Ken, Hasegawa, Yu, Nakagawa, Takashi, Katayama, Tetsuji, Sueta, Daisuke, Toyama, Kensuke, Kataoka, Keiichiro, Koibuchi, Nobutaka, Kuratsu, Jun-ichi, Kim-Mitsuyama, Shokei

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2013

23

Statins combined with exercise are associated with the increased renal function mediated by high-molecular-weight adiponectin in coronary artery disease patients

Toyama, Kensuke, Sugiyama, Seigo, Oka, Hideki, Iwasaki, Yuri, Sumida, Hitoshi, Tanaka, Tomoko, Tayama, Shinji, Jinnouchi, Hideaki, Ogawa, Hisao

Journal:

Journal of Cardiology

Année:

2014

Langue:

english

Fichier:

PDF, 968 KB

english, 2014

24

Blood pressure variability, impaired autonomic function and vascular senescence in aged spontaneously hypertensive rats are ameliorated by angiotensin blockade

Sueta, Daisuke, Koibuchi, Nobutaka, Hasegawa, Yu, Toyama, Kensuke, Uekawa, Ken, Katayama, Tetsuji, Ma, MingJie, Nakagawa, Takashi, Waki, Hidefumi, Maeda, Masanobu, Ogawa, Hisao, Kim-Mitsuyama, Shokei

Journal:

Atherosclerosis

Année:

2014

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2014

25

Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF

Nako, Hisato, Kataoka, Keiichiro, Koibuchi, Nobutaka, Dong, Yi-Fei, Toyama, Kensuke, Yamamoto, Eiichiro, Yasuda, Osamu, Ichijo, Hidenori, Ogawa, Hisao, Kim-Mitsuyama, Shokei

Journal:

Hypertension Research

Année:

2012

Langue:

english

Fichier:

PDF, 480 KB

english, 2012

26

Telmisartan enhances mitochondrial activity and alters cellular functions in human coronary artery endothelial cells via AMP-activated protein kinase pathway

Kurokawa, Hirofumi, Sugiyama, Seigo, Nozaki, Toshimitsu, Sugamura, Koichi, Toyama, Kensuke, Matsubara, Junichi, Fujisue, Koichiro, Ohba, Keisuke, Maeda, Hirofumi, Konishi, Masaaki, Akiyama, Eiichi, Su

Journal:

Atherosclerosis

Année:

2015

Langue:

english

Fichier:

PDF, 2.35 MB

english, 2015

27

DPP-4 inhibitor linagliptin ameliorates cardiovascular injury in salt-sensitive hypertensive rats independently of blood glucose and blood pressure

Koibuchi, Nobutaka, Hasegawa, Yu, Katayama, Tetsuji, Toyama, Kensuke, Uekawa, Ken, Sueta, Daisuke, Kusaka, Hiroaki, Ma, MingJie, Nakagawa, Takashi, Lin, Bowen, Kim-Mitsuyama, Shokei

Journal:

Cardiovascular Diabetology

Année:

2014

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2014

28

Therapy with the Combination of Amlodipine and Irbesartan Has Persistent Preventative Effects on Stroke Onset Associated with BDNF Preservation on Cerebral Vessels in Hypertensive Rats

Hasegawa, Yu, Nakagawa, Takashi, Uekawa, Ken, Ma, Mingjie, Lin, Bowen, Kusaka, Hiroaki, Katayama, Tetsuji, Sueta, Daisuke, Toyama, Kensuke, Koibuchi, Nobutaka, Kim-Mitsuyama, Shokei

Journal:

Translational Stroke Research

Année:

2016

Langue:

english

Fichier:

PDF, 544 KB

english, 2016

29

Glycemic control with empagliflozin, a novel selective SGLT2 inhibitor, ameliorates cardiovascular injury and cognitive dysfunction in obese and type 2 diabetic mice

Lin, Bowen, Koibuchi, Nobutaka, Hasegawa, Yu, Sueta, Daisuke, Toyama, Kensuke, Uekawa, Ken, Ma, MingJie, Nakagawa, Takashi, Kusaka, Hiroaki, Kim-Mitsuyama, Shokei

Journal:

Cardiovascular Diabetology

Année:

2014

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2014

30

Construct validity, reliability, response rate, and association with disease activity of the quick disabilities of the arm, shoulder and hand questionnaire in the assessment of rheumatoid arthritis

Ochi, Kensuke, Iwamoto, Takuji, Saito, Asami, Ikari, Katsunori, Toyama, Yoshiaki, Taniguchi, Atsuo, Yamanaka, Hisashi, Momohara, Shigeki

Journal:

Modern Rheumatology

Année:

2015

Langue:

english

Fichier:

PDF, 225 KB

english, 2015

31

Interfascicular Neurolysis for Incomplete Spontaneous Posterior Interosseous Nerve Palsy with a Surgical Delay of 17 Years: Is It Still Effective?

Ochi, Kensuke, Horiuchi, Yukio, Arino, Hiroshi, Toyama, Yoshiaki

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 722 KB

english, 2015

32

Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles

Ochi, Kensuke, Daigo, Yataro, Katagiri, Toyomasa, Nagayama, Satoshi, Tsunoda, Tatsuhiko, Myoui, Akira, Naka, Norifumi, Araki, Nobuto, Kudawara, Ikuo, Ieguchi, Makoto, Toyama, Yoshiaki, Toguchida, Juny

Journal:

International Journal of Oncology

Année:

2004

Langue:

english

Fichier:

PDF, 2.44 MB

english, 2004

33

Association Between Sleep Apnea, Sleep Duration, and Serum Lipid Profile in an Urban, Male, Working Population in Japan

Toyama, Yoshiro, Chin, Kazuo, Chihara, Yuichi, Takegami, Misa, Takahashi, Ken-ichi, Sumi, Kensuke, Nakamura, Takaya, Nakayama-Ashida, Yukiyo, Minami, Itsunari, Horita, Sachiko, Oka, Yasunori, Wakamura

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 227 KB

english, 2013

34

DPP-4 inhibition with linagliptin ameliorates cognitive impairment and brain atrophy induced by transient cerebral ischemia in type 2 diabetic mice

Ma, MingJie, Hasegawa, Yu, Koibuchi, Nobutaka, Toyama, Kensuke, Uekawa, Ken, Nakagawa, Takashi, Lin, Bowen, Kim-Mitsuyama, Shokei

Journal:

Cardiovascular Diabetology

Année:

2015

Langue:

english

Fichier:

PDF, 2.20 MB

english, 2015

35

Novel mechanism of salt-induced glomerular injury

Nakamura, Taishi, Kataoka, Keiichiro, Tokutomi, Yoshiko, Nako, Hisato, Toyama, Kensuke, Dong, Yi-Fei, Koibuchi, Nobutaka, Yamamoto, Eiichiro, Yasuda, Osamu, Ogawa, Hisao, Kim-Mitsuyama, Shokei

Journal:

Journal of Hypertension

Année:

2011

Langue:

english

Fichier:

PDF, 369 KB

english, 2011

36

Partial obturator nerve transfer for femoral nerve injury: A case report

Inaba, Naoto, Sato, Kazuki, Suzuki, Taku, Iwamoto, Takuji, Ochi, Kensuke, Nakamura, Masaya, Matsumoto, Morio, Toyama, Yoshiaki

Journal:

Journal of Orthopaedic Science

Année:

2016

Langue:

english

Fichier:

PDF, 954 KB

english, 2016

37

ASK1 is involved in cognitive impairment caused by long-term high-fat diet feeding in mice

Toyama, Kensuke, Koibuchi, Nobutaka, Hasegawa, Yu, Uekawa, Ken, Yasuda, Osamu, Sueta, Daisuke, Nakagawa, Takashi, Ma, Mingjie, Kusaka, Hiroaki, Lin, Bowen, Ogawa, Hisao, Ichijo, Hidenor, Kim-Mitsuyama

Journal:

Scientific Reports

Année:

2015

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2015

38

Sensorineural Hearing Loss Combined with Takayasu’s Arteritis

MARUYOSHI, Hidetomo, TOYAMA, Kensuke, KOJIMA, Sunao, KAWANO, Hiroaki, OGATA, Norihisa, MIYAMOTO, Shinzo, SAKAMOTO, Tomohiro, YOSHIMURA, Michihiro, OGAWA, Hisao

Journal:

Internal Medicine

Année:

2005

Langue:

english

Fichier:

PDF, 230 KB

english, 2005

39

Platypnea-Orthodeoxia Syndrome Combined with Multiple Congenital Heart Anomalies

NAGAYOSHI, Yasuhiro, TOYAMA, Kensuke, KAWANO, Hiroaki, MISUMI, Ikuo, MIYAMOTO, Shinzo, KOJIMA, Sunao, SAKAMOTO, Tomohiro, YOSHIMURA, Michihiro, OGAWA, Hisao

Journal:

Internal Medicine

Année:

2005

Langue:

english

Fichier:

PDF, 434 KB

english, 2005

40

Primary Systemic Amyloidosis with Bloody Pericardial Effusion

Toyama, Kensuke, Oka, Hideki, Obata, Kenji, Ogawa, Hisao

Journal:

Internal Medicine

Année:

2009

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2009

41

Primary Systemic Amyloidosis with Bloody Pericardial Effusion

Toyama, Kensuke, Oka, Hideki, Obata, Kenji, Ogawa, Hisao

Journal:

Internal Medicine

Année:

2009

Fichier:

PDF, 44 KB

2009

42

A therapeutic benefit of daptomycin against glycopeptide-resistant gram-positive cocci bloodstream infections under neutropenia

Matsuda, Kensuke, Koya, Junji, Toyama, Kazuhiro, Ikeda, Mahoko, Arai, Shunya, Nakamura, Fumihiko, Okugawa, Shu, Moriya, Kyoji, Kurokawa, Mineo

Journal:

Journal of Infection and Chemotherapy

Année:

2017

Langue:

english

Fichier:

PDF, 408 KB

english, 2017

43

Erratum: Erratum: ASK1 is involved in cognitive impairment caused by long-term high-fat diet feeding in mice

Toyama, Kensuke, Koibuchi, Nobutaka, Hasegawa, Yu, Uekawa, Ken, Yasuda, Osamu, Sueta, Daisuke, Nakagawa, Takashi, Ma, Mingjie, Kusaka, Hiroaki, Lin, Bowen, Ogawa, Hisao, Ichijo, Hidenori, Kim-Mitsuyam

Journal:

Scientific Reports

Année:

2015

Langue:

english

Fichier:

PDF, 313 KB

english, 2015

44

Intermittent Compressive Strain May Reduce Aggrecanase Expression in Cartilage

Mio, Kensuke, Saito, Seiji, Tomatsu, Taisuke, Toyama, Yoshiaki

Journal:

Clinical Orthopaedics and Related Research®

Année:

2005

Langue:

english

Fichier:

PDF, 471 KB

english, 2005

45

Role of ASK1/p38 Cascade in a Mouse Model of Alzheimer’s Disease and Brain Aging

Hasegawa, Yu, Toyama, Kensuke, Uekawa, Ken, Ichijo, Hidenori, Kim-Mitsuyama, Shokei

Journal:

Journal of Alzheimer's Disease

Année:

2017

Langue:

english

Fichier:

PDF, 366 KB

english, 2017

46

Role of microRNAs on Blood Brain Barrier Dysfunction in Vascular Cognitive Impairment

Toyama, Kensuke, Spin, Joshua Michael, Tsao, Philip Shih

Journal:

Current Drug Delivery

Année:

2017

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2017

47

MicroRNA-Mediated Therapy Modulating Blood–Brain Barrier Disruption Improves Vascular Cognitive Impairment

Toyama, Kensuke, Spin, Joshua M., Deng, Alicia C., Huang, Ting-Ting, Wei, Ke, Wagenhäuser, Markus U., Yoshino, Takuya, Nguyen, Huy, Mulorz, Joscha, Kundu, Soumajit, Raaz, Uwe, Adam, Matti, Schellinger

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Année:

2018

Langue:

english

Fichier:

PDF, 8.17 MB

english, 2018

48

A Pilot Study: The Beneficial Effects of Combined Statin-exercise Therapy on Cognitive Function in Patients with Coronary Artery Disease and Mild Cognitive Decline

Toyama, Kensuke, Sugiyama, Seigo, Oka, Hideki, Hamada, Mari, Iwasaki, Yuri, Horio, Eiji, Rokutanda, Taku, Nakamura, Shinichi, Spin, Joshua M., Tsao, Philip S., Ogawa, Hisao

Journal:

Internal Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 286 KB

english, 2017

49

Systemic Upregulation of IL-10 (Interleukin-10) Using a Nonimmunogenic Vector Reduces Growth and Rate of Dissecting Abdominal Aortic Aneurysm

Adam, Matti, Kooreman, Nigel, Jagger, Ann, Wagenhaeuser, Markus U, Mehrkens, Dennis, Wang, Yongming, Kayama, Yosuke, Toyama, Kensuke, Raaz, Uwe, Schellinger, Isabel N., Maegdefessel, Lars, Spin, Joshu

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Année:

2018

Langue:

english

Fichier:

PDF, 2.21 MB

english, 2018

50

Combination Treatment of Rosuvastatin or Atorvastatin, with Regular Exercise Improves Arterial Wall Stiffness in Patients with Coronary Artery Disease

Toyama, Kensuke, Sugiyama, Seigo, Oka, Hideki, Iwasaki, Yuri, Sumida, Hitoshi, Tanaka, Tomoko, Tayama, Shinji, Jinnouchi, Hideaki, Ogawa, Hisao, Aikawa, Elena

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 474 KB

english, 2012